Diabetes Insipidus: Pathogenesis, Diagnosis, and Clinical Management

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Diabetes insipidus--diagnosis and management.

Central diabetes insipidus (CDI) is the end result of a number of conditions that affect the hypothalamic-neurohypophyseal system. The known causes include germinoma/craniopharyngioma, Langerhans cell histiocytosis (LCH), local inflammatory, autoimmune or vascular diseases, trauma resulting from surgery or an accident, sarcoidosis, metastases and midline cerebral and cranial malformations. In r...

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Water! Water! Everywhere! Diagnosis and Management of Nephrogenic Diabetes Insipidus

Goals: 1. Understand diabetes insipidus and the role of arginine vasopressin production and its role at the kidney 2. Understand how to differentiate nephrogenic diabetes insipidus from central diabetes insipidus and primary polydipsia 3. Understand the etiology of nephrogenic diabetes insipidus 4. Understand the available diagnostic tools and their usefulness in characterizing the picture of n...

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Physiopathology and diagnosis of nephrogenic diabetes insipidus.

Nephrogenic diabetes insipidus (NDI) is caused by an improper response of the kidney to the antidiuretic hormone arginine vasopressin (AVP), leading to a decreased ability to concentrate urine which results in polyuria and polydipsia. The clinical diagnosis of NDI relies on demonstration of subnormal ability to concentrate urine despite the presence of AVP. NDI is most commonly acquired, second...

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Clinical review: Current state and future perspectives in the diagnosis of diabetes insipidus: a clinical review.

CONTEXT The differential diagnosis of diabetes insipidus (DI) is often challenging but essential, because treatment may vary substantially. This article analyzes the database and performance of currently used differential diagnostic tests for DI and discusses future perspectives for diagnostic improvement. EVIDENCE ACQUISITION A review of electronic and print data comprising original and revi...

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Diabetes Insipidus and Trauma (15 Cases Report)

SUMMARY In a survey during a period of 3 years (1363 -1366), we have studied 15 Patients with diabetes insipidus due to accidents, measless and surgery. Finally, after this period we find that permanent diabetes insipid us was clear in (2 head. injury, 2 patients with head measle, and two after surgery for craniopharyngioma). In eight rest patients diabetes insipid us was temporary and subside...

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ژورنال

عنوان ژورنال: Cureus

سال: 2021

ISSN: 2168-8184

DOI: 10.7759/cureus.13523